Human ERLIN2 (ER Lipid Raft Associated Protein 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015081)

Human ERLIN2 (ER Lipid Raft Associated Protein 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015081)

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STJE0015081
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.115ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This ERLIN2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ERLIN2
Gene ID: 11160
Uniprot ID: ERLN2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Ubiquitous.
Post Translational Modifications Deubiquitinated by USP25.leading to stabilization.
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.
Protein Name Erlin-2
Endoplasmic Reticulum Lipid Raft-Associated Protein 2
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2
Spfh Domain-Containing Protein 2
Database Links Reactome: R-HSA-382556
Reactome: R-HSA-5655302
Reactome: R-HSA-5678895
Reactome: R-HSA-8853336
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane
Alternative ELISA Names Erlin-2 ELISA kit
Endoplasmic Reticulum Lipid Raft-Associated Protein 2 ELISA kit
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2 ELISA kit
Spfh Domain-Containing Protein 2 ELISA kit
ERLIN2 ELISA kit
C8orf2 ELISA kit
SPFH2 ELISA kit
UNQ2441 ELISA kit
PRO5003 ELISA kit
PRO9924 ELISA kit
output

Information sourced from Uniprot.org

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