Human ERC1 protein (Recombinant) (N-His-SUMO) (STJP009662)

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STJP009662
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ERC1-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ERC1
Gene ID: 23085
Uniprot ID: RB6I2_HUMAN
Immunogen Region: Lys1003-Ser1116
Immunogen: Homo sapiens (Human)
Function Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.
Protein Name Elks/Rab6-Interacting/Cast Family Member 1
Erc-1
Rab6-Interacting Protein 2
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Membrane
Peripheral Membrane Protein
Golgi Apparatus Membrane
Presynaptic Cell Membrane
Cell Projection
Podosome
Recruited On Golgi Membranes By Rab6a In A Gtp-Dependent Manner
Localized To The Cortex Of Myotube Podosomes
Alternative Protein Names Elks/Rab6-Interacting/Cast Family Member 1 protein
Erc-1 protein
Rab6-Interacting Protein 2 protein
ERC1 protein
ELKS protein
KIAA1081 protein
RAB6IP2 protein

Information sourced from Uniprot.org

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