| Tissue Specificity | Found in liver. |
| Post Translational Modifications | |
| Function | Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. Binds 20(S)-hydroxycholesterol (20(S)-OHC). |
| Protein Name | Epoxide Hydrolase 1Epoxide HydrataseMicrosomal Epoxide HydrolaseMeh |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Iii Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative ELISA Names | Epoxide Hydrolase 1 ELISA kitEpoxide Hydratase ELISA kitMicrosomal Epoxide Hydrolase ELISA kitMeh ELISA kitEPHX1 ELISA kitEPHX ELISA kitEPOX ELISA kit |
| output | |
Information sourced from Uniprot.org