Human EPB41 protein (Recombinant) (N-His) (STJP003991)

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STJP003991
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human EPB41-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: EPB41
Gene ID: 2035
Uniprot ID: EPB41_HUMAN
Immunogen Region: Met210-Lys497
Immunogen: Homo sapiens (Human)
Function Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
Protein Name Protein 4.1
P4.1
4.1r
Band 4.1
Epb4.1
Erythrocyte Membrane Protein Band 4.1
Database Links Reactome: R-HSA-6794361
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Cortex
Nucleus
Alternative Protein Names Protein 4.1 protein
P4.1 protein
4.1r protein
Band 4.1 protein
Epb4.1 protein
Erythrocyte Membrane Protein Band 4.1 protein
EPB41 protein
E41P protein

Information sourced from Uniprot.org