Function | Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. |
Protein Name | Protein 4.1P4.14.1rBand 4.1Epb4.1Erythrocyte Membrane Protein Band 4.1 |
Database Links | Reactome: R-HSA-6794361 |
Cellular Localisation | CytoplasmCytoskeletonCell CortexNucleus |
Alternative Protein Names | Protein 4.1 proteinP4.1 protein4.1r proteinBand 4.1 proteinEpb4.1 proteinErythrocyte Membrane Protein Band 4.1 proteinEPB41 proteinE41P protein |
Information sourced from Uniprot.org