| Tissue Specificity | Expressed in CD8+ T-cells. |
| Post Translational Modifications | |
| Function | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Required for differentiation and migration of unipolar dendritic brush cells. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. |
| Protein Name | Eomesodermin HomologT-Box Brain Protein 2T-Brain-2Tbr-2 |
| Database Links | Reactome: R-HSA-9733709Reactome: R-HSA-9754189Reactome: R-HSA-9758919Reactome: R-HSA-9823730Reactome: R-HSA-9827857 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Eomesodermin Homolog ELISA kitT-Box Brain Protein 2 ELISA kitT-Brain-2 ELISA kitTbr-2 ELISA kitEOMES ELISA kitTBR2 ELISA kit |
| output | |
Information sourced from Uniprot.org
