| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1.0 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | PROCR |
| Gene ID: | 10544 |
| Uniprot ID: | EPCR_HUMAN |
| Immunogen: | Recombinant Human Endothelial protein C receptor/CD201 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser18-Ser210) of human EPCR/CD201/PROCR (Accession #NP_006395.2) fused with a 6×His tag at th |
| Immunogen Sequence: | SQDASDGLQRLHMLQISYFR DPYHVWYQGNASLGGHLTHV LEGPDTNTTIIQLQPLQEPE SWARTQSGLQSYLLQFHGLV RLVHQERTLAFPLTIRCFLG CELPPEGSRAHVFFEVAVNG SSFVSFRPERALWQADTQVT SGVVTFTLQQLNAYNRTRYE LREFLEDTCVQYVQKHISAE NTKGSQTSRSYTS |
| Post Translational Modifications | N-glycosylated. A soluble form exists.probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form. |
| Function | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex.plays a role in the protein C pathway controlling blood coagulation. |
| Protein Name | Endothelial Protein C ReceptorActivated Protein C ReceptorApc ReceptorEndothelial Cell Protein C ReceptorCd Antigen Cd201 |
| Database Links | Reactome: R-HSA-140875Reactome: R-HSA-202733 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Endothelial Protein C Receptor proteinActivated Protein C Receptor proteinApc Receptor proteinEndothelial Cell Protein C Receptor proteinCd Antigen Cd201 proteinPROCR proteinEPCR protein |
Information sourced from Uniprot.org
