| Short Description : | Recombinant-Human ELP4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ELP4 |
| Gene ID: | 26610 |
| Uniprot ID: | ELP4_HUMAN |
| Accession Number: | NP_061913 |
| Immunogen: | Human |
| Immunogen Region: | 1-424aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAAVATC GSVAASTGSA VATASKSNVT SFQRRGPRAS VTNDSGPRLV SIAGTRPSVR NGQLLVSTGL PALDQLLGGG LAVGTVLLIE EDKYNIYSPL LFKYFLAEGI VNGHTLLVAS AKEDPANILQ ELPAPLLDDK CKKEFDEDVY NHKTPESNIK MKIAWRYQLL PKMEIGPVSS SRFGHYYDAS KRMPQELIEA SNWHGFFL |
| Tissue Specificity | Widely expressed. |
| Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. |
| Protein Name | Elongator Complex Protein 4Help4Pax6 Neighbor Gene Protein |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Elongator Complex Protein 4 proteinHelp4 proteinPax6 Neighbor Gene Protein proteinELP4 proteinC11orf19 proteinPAXNEB protein |
Information sourced from Uniprot.org
