| Function | ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. |
| Protein Name | Eh Domain-Containing Protein 2Past Homolog 2 |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideMembraneCaveolaEndosome MembraneCytoplasmCytosolColocalizes With Glut4 In Intracellular Tubulovesicular Structures That Are Associated With Cortical F-ActinColocalizes With Fer1l5 At Plasma Membrane In Myoblasts And Myotubes |
| Alternative Protein Names | Eh Domain-Containing Protein 2 proteinPast Homolog 2 proteinEHD2 proteinPAST2 protein |
Information sourced from Uniprot.org
