| Short Description : | Recombinant-Active-Human EFNA4-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Immobilised human EphA7 at 0.5 Mu g/mL (100 Mu L/well) can bind human EFNA4 with a linear range of 0.039-0.942 ng/mL. |
| Gene Symbol: | EFNA4 |
| Gene ID: | 1945 |
| Uniprot ID: | EFNA4_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Leu26-Gly171 |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils. |
| Protein Name | Ephrin-A4Eph-Related Receptor Tyrosine Kinase Ligand 4Lerk-4 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
| Alternative Protein Names | Ephrin-A4 proteinEph-Related Receptor Tyrosine Kinase Ligand 4 proteinLerk-4 proteinEFNA4 proteinEPLG4 proteinLERK4 protein |
Information sourced from Uniprot.org
