Human EFNA4 protein (Recombinant-Active) (C-hFc-His) (STJP012027)

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STJP012027-100
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Covered by St John's Laboratory Guarantee

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human EFNA4-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: EFNA4
Gene ID: 1945
Uniprot ID: EFNA4_HUMAN
Immunogen Region: Leu26-Gly171
Immunogen: Homo sapiens (Human)
Function Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
Protein Name Ephrin-A4
Eph-Related Receptor Tyrosine Kinase Ligand 4
Lerk-4
Database Links Reactome: R-HSA-2682334
Reactome: R-HSA-3928663
Reactome: R-HSA-3928665
Cellular Localisation Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Protein Names Ephrin-A4 protein
Eph-Related Receptor Tyrosine Kinase Ligand 4 protein
Lerk-4 protein
EFNA4 protein
EPLG4 protein
LERK4 protein

Information sourced from Uniprot.org

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