Human EFNA3 protein (Recombinant-Active) (C-His) (STJP012026)

SKU:
STJP012026-100
€691.88
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human EFNA3-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: EFNA3
Gene ID: 1944
Uniprot ID: EFNA3_HUMAN
Immunogen Region: Met1-Ser213
Immunogen: Homo sapiens (Human)
Function Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
Protein Name Ephrin-A3
Efl-2
Ehk1 Ligand
Ehk1-L
Eph-Related Receptor Tyrosine Kinase Ligand 3
Lerk-3
Database Links Reactome: R-HSA-2682334
Reactome: R-HSA-3928663
Reactome: R-HSA-3928665
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Protein Names Ephrin-A3 protein
Efl-2 protein
Ehk1 Ligand protein
Ehk1-L protein
Eph-Related Receptor Tyrosine Kinase Ligand 3 protein
Lerk-3 protein
EFNA3 protein
EFL2 protein
EPLG3 protein
LERK3 protein

Information sourced from Uniprot.org