Human EEF1A2 protein (Recombinant) (N-His) (STJP005190)

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STJP005190
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Short Description :Recombinant-Human EEF1A2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:EEF1A2
Gene ID:1917
Uniprot ID:EF1A2_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Gly213-Lys463
Post Translational Modifications Trimethylated at Lys-165 by EEF1AKMT3. Mono-, di-, and trimethylated at Lys-36 by EEF1AKMT4.trimethylated form is predominant. Methylation by EEF1AKMT4 contributes to the fine-tuning of translation rates for a subset of tRNAs. Trimethylated at the N-terminus by METTL13. Mono- and dimethylated at Lys-55 by METTL13.dimethylated form is predominant.
Function Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis. Base pairing between the mRNA codon and the aa-tRNA anticodon promotes GTP hydrolysis, releasing the aa-tRNA from EEF1A1 and allowing its accommodation into the ribosome. The growing protein chain is subsequently transferred from the P-site peptidyl tRNA to the A-site aa-tRNA, extending it by one amino acid through ribosome-catalyzed peptide bond formation.
Protein Name Elongation Factor 1-Alpha 2
Ef-1-Alpha-2
Eukaryotic Elongation Factor 1 A-2
Eef1a-2
Statin-S1
Database Links Reactome: R-HSA-156842
Cellular Localisation Endoplasmic Reticulum Membrane
Alternative Protein Names Elongation Factor 1-Alpha 2 protein
Ef-1-Alpha-2 protein
Eukaryotic Elongation Factor 1 A-2 protein
Eef1a-2 protein
Statin-S1 protein
EEF1A2 protein
EEF1AL protein
STN protein

Information sourced from Uniprot.org

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