| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ECRG4-N-His-KSI protein was developed from e. coli and has a target region of N-His-KSI. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | ECRG4 |
| Gene ID: | 84417 |
| Uniprot ID: | AUGN_HUMAN |
| Immunogen Region: | Asn32-Tyr148 |
| Immunogen: | Homo sapiens (Human) |
| Function | Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation. |
| Protein Name | AugurinEsophageal Cancer-Related Gene 4 ProteinEcrg4 |
| Cellular Localisation | SecretedCytoplasmApical Cell Membrane |
| Alternative Protein Names | Augurin proteinEsophageal Cancer-Related Gene 4 Protein proteinEcrg4 proteinECRG4 proteinC2orf40 proteinUNQ761 proteinPRO1508 protein |
Information sourced from Uniprot.org