Tissue Specificity | Expressed in the intermediate lobe of pituitary, glomerular layer of adrenal cortex, choroid plexus and atrioventricular node of the heart. Expressed in the brain with high expression in the choroid plexus and the epithelial lining of the central canal and expression in the gray matter of the spinal cord (at protein level). |
Post Translational Modifications | |
Function | Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation. |
Protein Name | AugurinEsophageal Cancer-Related Gene 4 Protein Homolog |
Database Links | |
Cellular Localisation | SecretedCytoplasmApical Cell Membrane |
Alternative ELISA Names | Augurin ELISA kitEsophageal Cancer-Related Gene 4 Protein Homolog ELISA kitEcrg4 ELISA kit |
output | |
Information sourced from Uniprot.org