| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Biotin |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | SELE |
| Gene ID: | 6401 |
| Uniprot ID: | LYAM2_HUMAN |
| Immunogen Region: | Trp22-Pro556 |
| Immunogen: | Biotinylated Recombinant Human E-Selectin/SELE/CD62E Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp22-Pro556) of Human E-Selectin/SELE/CD62E (Accession #P16581) fused with a C-His&Avi tag at |
| Immunogen Sequence: | WSYNTSTEAMTYDEASAYCQ QRYTHLVAIQNKEEIEYLNS ILSYSPSYYWIGIRKVNNVW VWVGTQKPLTEEAKNWAPGE PNNRQKDEDCVEIYIKREKD VGMWNDERCSKKKLALCYTA ACTNTSCSGHGECVETINNY TCKCDPGFSGLKCEQIVNCT ALESPEHGSLVCSHPLGNFS YNSSCSISCDRGYLPSSMET MQCMSSGEWSAPIPACNVVE CDAVTNPANGFVECFQNPG |
| Function | Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. |
| Protein Name | E-SelectinCd62 Antigen-Like Family Member EEndothelial Leukocyte Adhesion Molecule 1Elam-1Leukocyte-Endothelial Cell Adhesion Molecule 2Lecam2Cd Antigen Cd62e |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | E-Selectin proteinCd62 Antigen-Like Family Member E proteinEndothelial Leukocyte Adhesion Molecule 1 proteinElam-1 proteinLeukocyte-Endothelial Cell Adhesion Molecule 2 proteinLecam2 proteinCd Antigen Cd62e proteinSELE proteinELAM1 protein |
Information sourced from Uniprot.org
