Tissue Specificity | Highly expressed in brain, kidney and pancreas. |
Post Translational Modifications | Phosphorylated by PKA. Phosphorylation at Thr-11 alters the interaction with KIF5A. |
Function | Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids. May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses. |
Protein Name | Dystrobrevin BetaDtn-BBeta-Dystrobrevin |
Database Links | |
Cellular Localisation | CytoplasmPostsynaptic DensityCell ProjectionDendriteBasal Cell MembranePostsynapseNucleusLocalized At Inhibitory Synapses On The Dendrites Of Cerebellar Purkinje Cells |
Alternative ELISA Names | Dystrobrevin Beta ELISA kitDtn-B ELISA kitBeta-Dystrobrevin ELISA kitDTNB ELISA kit |
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Information sourced from Uniprot.org