| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human DSG1/Desmoglein-1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | DSG1 |
| Gene ID: | 1828 |
| Uniprot ID: | DSG1_HUMAN |
| Immunogen Region: | Asp264-Ser485 |
| Immunogen: | Homo sapiens (Human) |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-1Cadherin Family Member 4Desmosomal Glycoprotein 1Dg1DgiPemphigus Foliaceus Antigen |
| Database Links | Reactome: R-HSA-351906Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9696264Reactome: R-HSA-9696270 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosomeCytoplasmNucleus |
| Alternative Protein Names | Desmoglein-1 proteinCadherin Family Member 4 proteinDesmosomal Glycoprotein 1 proteinDg1 proteinDgi proteinPemphigus Foliaceus Antigen proteinDSG1 proteinCDHF4 protein |
Information sourced from Uniprot.org