Human DSC2 protein (Recombinant) (N-His) (STJP005155)

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STJP005155
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DSC2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DSC2
Gene ID: 1824
Uniprot ID: DSC2_HUMAN
Immunogen Region: Arg136-Cys471
Immunogen: Homo sapiens (Human)
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. May promote p38MAPK signaling activation that facilitates keratinocyte migration.
Protein Name Desmocollin-2
Cadherin Family Member 2
Desmocollin-3
Desmosomal Glycoprotein Ii
Desmosomal Glycoprotein Iii
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Alternative Protein Names Desmocollin-2 protein
Cadherin Family Member 2 protein
Desmocollin-3 protein
Desmosomal Glycoprotein Ii protein
Desmosomal Glycoprotein Iii protein
DSC2 protein
CDHF2 protein
DSC3 protein

Information sourced from Uniprot.org

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