Human DRD2 protein (Recombinant) (N-His) (STJP004097)

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STJP004097
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DRD2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DRD2
Gene ID: 1813
Uniprot ID: DRD2_HUMAN
Immunogen Region: Lys221-Gln373
Immunogen: Homo sapiens (Human)
Post Translational Modifications Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8.
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
Protein Name D(2 Dopamine Receptor
Dopamine D2 Receptor
Database Links Reactome: R-HSA-390651
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Protein Names D(2 Dopamine Receptor protein
Dopamine D2 Receptor protein
DRD2 protein

Information sourced from Uniprot.org