Human DPP8 (Dipeptidyl Peptidase 8) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014875)

Human DPP8 (Dipeptidyl Peptidase 8) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014875)

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STJE0014875
€605.63 - €833.13
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.117ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This DPP8 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: DPP8
Gene ID: 54878
Uniprot ID: DPP8_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain.
Post Translational Modifications
Function Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Acts as a key inhibitor of caspase-1-dependent monocyte and macrophage pyroptosis in resting cells by preventing activation of NLRP1 and CARD8. Sequesters the cleaved C-terminal part of NLRP1 and CARD8, which respectively constitute the active part of the NLRP1 and CARD8 inflammasomes, in a ternary complex, thereby preventing their oligomerization and activation. The dipeptidyl peptidase activity is required to suppress NLRP1 and CARD8.however, neither NLRP1 nor CARD8 are bona fide substrates of DPP8, suggesting the existence of substrate(s) required for NLRP1 and CARD8 inhibition.
Protein Name Dipeptidyl Peptidase 8
Dp8
Dipeptidyl Peptidase Iv-Related Protein 1
Dprp-1
Dipeptidyl Peptidase Viii
Dpp Viii
Prolyl Dipeptidase Dpp8
Database Links
Cellular Localisation Cytoplasm
Alternative ELISA Names Dipeptidyl Peptidase 8 ELISA kit
Dp8 ELISA kit
Dipeptidyl Peptidase Iv-Related Protein 1 ELISA kit
Dprp-1 ELISA kit
Dipeptidyl Peptidase Viii ELISA kit
Dpp Viii ELISA kit
Prolyl Dipeptidase Dpp8 ELISA kit
DPP8 ELISA kit
DPRP1 ELISA kit
MSTP097 ELISA kit
MSTP135 ELISA kit
MSTP141 ELISA kit
output

Information sourced from Uniprot.org

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