Tissue Specificity | |
Post Translational Modifications | |
Function | Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide. A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance. |
Protein Name | Dipeptidase 3 |
Database Links | Reactome: R-HSA-2142691Reactome: R-HSA-5423646Reactome: R-HSA-9664535 |
Cellular Localisation | MembraneLipid-AnchorGpi-Anchor |
Alternative ELISA Names | Dipeptidase 3 ELISA kitDPEP3 ELISA kitUNQ834 ELISA kitPRO1772 ELISA kit |
output | |
Information sourced from Uniprot.org