Human DPEP1 protein (Recombinant) (N-His) (STJP004168)

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STJP004168
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DPEP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DPEP1
Gene ID: 1800
Uniprot ID: DPEP1_HUMAN
Immunogen Region: Asp17-Leu411
Immunogen: Homo sapiens (Human)
Function Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
Protein Name Dipeptidase 1
Beta-Lactamase
Dehydropeptidase-I
Microsomal Dipeptidase
Renal Dipeptidase
Hrdp
Database Links Reactome: R-HSA-2142691
Reactome: R-HSA-5423646
Reactome: R-HSA-9664535
Cellular Localisation Apical Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cell Projection
Microvillus Membrane
Brush Border Membrane
Alternative Protein Names Dipeptidase 1 protein
Beta-Lactamase protein
Dehydropeptidase-I protein
Microsomal Dipeptidase protein
Renal Dipeptidase protein
Hrdp protein
DPEP1 protein
MDP protein
RDP protein

Information sourced from Uniprot.org

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