Human DOC2A protein (Recombinant) (N-His) (STJP005385)

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STJP005385
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DOC2A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DOC2A
Gene ID: 8448
Uniprot ID: DOC2A_HUMAN
Immunogen Region: Ile11-Gln241
Immunogen: Homo sapiens (Human)
Function Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
Protein Name Double C2-Like Domain-Containing Protein Alpha
Doc2
Doc2-Alpha
Cellular Localisation Lysosome
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Peripheral Membrane Protein
Synapse
Synaptosome
Alternative Protein Names Double C2-Like Domain-Containing Protein Alpha protein
Doc2 protein
Doc2-Alpha protein
DOC2A protein

Information sourced from Uniprot.org

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