| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human DNASE1L2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | DNASE1L2 |
| Gene ID: | 1775 |
| Uniprot ID: | DNSL2_HUMAN |
| Immunogen Region: | Ala21-Arg299 |
| Immunogen: | Homo sapiens (Human) |
| Function | Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells. |
| Protein Name | Deoxyribonuclease-1-Like 2Dnase I Homolog Protein Dhp1Deoxyribonuclease I-Like 2Dnase I-Like 2 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative Protein Names | Deoxyribonuclease-1-Like 2 proteinDnase I Homolog Protein Dhp1 proteinDeoxyribonuclease I-Like 2 proteinDnase I-Like 2 proteinDNASE1L2 proteinDHP1 proteinDNAS1L2 protein |
Information sourced from Uniprot.org