Tissue Specificity | Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. |
Post Translational Modifications | Ubiquitinated, leading to its degradation. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells. |
Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. |
Protein Name | Disks Large-Associated Protein 5Dap-5Discs Large Homolog 7Disks Large-Associated Protein Dlg7Hepatoma Up-Regulated ProteinHurp |
Database Links | Reactome: R-HSA-9013508 |
Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleLocalizes To The Spindle In Mitotic CellsColocalizes With Cdh1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells |
Alternative ELISA Names | Disks Large-Associated Protein 5 ELISA kitDap-5 ELISA kitDiscs Large Homolog 7 ELISA kitDisks Large-Associated Protein Dlg7 ELISA kitHepatoma Up-Regulated Protein ELISA kitHurp ELISA kitDLGAP5 ELISA kitDLG7 ELISA kitKIAA0008 ELISA kit |
output | |
Information sourced from Uniprot.org