Human DIXDC1 protein (Recombinant) (N-His) (STJP005460)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human DIXDC1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | DIXDC1 |
| Gene ID | 85458 |
| Uniprot ID | DIXC1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser485-Asn683 |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosine and serine residues. Polyubiquitinated, leading to its proteasomal degradation. WNT3A signaling increases DIXDC1 protein levels by inhibiting its ubiquitination and subsequent degradation. |
| Function | Positive effector of the Wnt signaling pathway.activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2. |
| Protein Name | DixinCoiled-Coil Protein Dix1Coiled-Coil-Dix1Dix Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | Cell JunctionFocal AdhesionCytoplasmCytoskeletonStress FiberColocalizes With Gamma-Tubulin At The CentrosomeBoth During Interphase And MitosisAssociated With Actin Stress Fiber At The Filament EndsIsoform 2: CytoplasmNot Associated With Stress Fibers |
| Alternative Protein Names | Dixin proteinCoiled-Coil Protein Dix1 proteinCoiled-Coil-Dix1 proteinDix Domain-Containing Protein 1 proteinDIXDC1 proteinCCD1 proteinKIAA1735 protein |
Information sourced from Uniprot.org