| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human DEPDC1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | DEPDC1 |
| Gene ID: | 55635 |
| Uniprot ID: | DEP1A_HUMAN |
| Immunogen Region: | Phe138-Leu248 |
| Immunogen: | Homo sapiens (Human) |
| Function | May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. |
| Protein Name | Dep Domain-Containing Protein 1a |
| Cellular Localisation | NucleusColocalizes With Znf224 At The Nucleus |
| Alternative Protein Names | Dep Domain-Containing Protein 1a proteinDEPDC1 proteinDEPDC1A protein |
Information sourced from Uniprot.org