Human DCT protein (Recombinant) (N-His) (STJP004671)

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STJP004671
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DCT-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DCT
Gene ID: 1638
Uniprot ID: TYRP2_HUMAN
Immunogen Region: Val28-Gly263
Immunogen: Homo sapiens (Human)
Function Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
Protein Name L-Dopachrome Tautomerase
Dct
Dt
L-Dopachrome Delta-Isomerase
Tyrosinase-Related Protein 2
Trp-2
Trp2
Database Links Reactome: R-HSA-5662702
Reactome: R-HSA-9824585
Cellular Localisation Melanosome Membrane
Single-Pass Type I Membrane Protein
Melanosome
Proper Trafficking To Melanosome Is Regulated By Sgsm2
Ankrd27
Rab9a
Rab32 And Rab38
Alternative Protein Names L-Dopachrome Tautomerase protein
Dct protein
Dt protein
L-Dopachrome Delta-Isomerase protein
Tyrosinase-Related Protein 2 protein
Trp-2 protein
Trp2 protein
DCT protein
TYRP2 protein

Information sourced from Uniprot.org