Human DCAF7 protein (Recombinant) (His-Tag) (STJP017305)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DCAF7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DCAF7 |
| Gene ID | 10238 |
| Uniprot ID | DCAF7_HUMAN |
| Accession Number | NP_005819 |
| Immunogen | Human |
| Immunogen Region | 19-295aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MVYAMNWSVR PDKRFRLALG SFVEEYNNKV QLVGLDEESS EFICRNTFDH PYPTTKLMWI PDTKGVYPDL LATSGDYLRV WRVGETETRL ECLLNNNKNS DFCAPLTSFD WNEVDPYLLG TSSIDTTCTI WGLETGQVLG RVNLVSGHVK TQLIAHDKEV YDIAFSRAGG GRDMFASVGA DGSVRMFDLR HLEHSTIIYE DPQHHPLL |
Additional Info
| Function | Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
| Protein Name | Ddb1- And Cul4-Associated Factor 7Wd Repeat-Containing Protein 68Wd Repeat-Containing Protein An11 Homolog |
| Database Links | Reactome: R-HSA-390471Reactome: R-HSA-8951664 |
| Cellular Localisation | CytoplasmNucleusOverexpression Of Diahp1 Or Active Rhoa Causes Translocation From The Nucleus To Cytoplasm |
| Alternative Protein Names | Ddb1- And Cul4-Associated Factor 7 proteinWd Repeat-Containing Protein 68 proteinWd Repeat-Containing Protein An11 Homolog proteinDCAF7 proteinHAN11 proteinWDR68 protein |
Information sourced from Uniprot.org