Human DCAF7 protein (Recombinant) (His-Tag) (STJP017305)

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STJP017305
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DCAF7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 1mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: DCAF7
Gene ID: 10238
Uniprot ID: DCAF7_HUMAN
Immunogen Region: 19-295aa
Accession Number: NP_005819
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MVYAMNWSVR PDKRFRLALG SFVEEYNNKV QLVGLDEESS EFICRNTFDH PYPTTKLMWI PDTKGVYPDL LATSGDYLRV WRVGETETRL ECLLNNNKNS DFCAPLTSFD WNEVDPYLLG TSSIDTTCTI WGLETGQVLG RVNLVSGHVK TQLIAHDKEV YDIAFSRAGG GRDMFASVGA DGSVRMFDLR HLEHSTIIYE DPQHHPLL
Function Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Protein Name Ddb1- And Cul4-Associated Factor 7
Wd Repeat-Containing Protein 68
Wd Repeat-Containing Protein An11 Homolog
Database Links Reactome: R-HSA-390471
Reactome: R-HSA-8951664
Cellular Localisation Cytoplasm
Nucleus
Overexpression Of Diahp1 Or Active Rhoa Causes Translocation From The Nucleus To Cytoplasm
Alternative Protein Names Ddb1- And Cul4-Associated Factor 7 protein
Wd Repeat-Containing Protein 68 protein
Wd Repeat-Containing Protein An11 Homolog protein
DCAF7 protein
HAN11 protein
WDR68 protein

Information sourced from Uniprot.org

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