Name: Human CYP3A7 protein (Recombinant) (N-His) (STJP004399)
SKU: STJP004399
Availability: InStock

Human CYP3A7 protein (Recombinant) (N-His) (STJP004399)

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STJP004399

£208.50 - £1,163.50

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Short Description :	Recombinant-Human CYP3A7-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Metabolizes 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone, DHEA), a precursor in the biosynthesis of androgen and estrogen steroid hormones. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1), particularly D-ring hydroxylated estrone at the C16-alpha position. Mainly hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may play a role in atRA clearance during fetal development. Also involved in the oxidative metabolism of xenobiotics including anticonvulsants.
Protein Name	Cytochrome P450 3a7 Cypiiia7 Cytochrome P450-Hfla P450hlp2
Database Links	Reactome: R-HSA-211981
Cellular Localisation	Endoplasmic Reticulum Membrane Peripheral Membrane Protein Microsome Membrane
Alternative Protein Names	Cytochrome P450 3a7 protein Cypiiia7 protein Cytochrome P450-Hfla protein P450hlp2 protein CYP3A7 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP015118	Human TAS1R1 protein protein (Recombinant) (N-His) (STJP015118)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP007174	Human MUC2 protein (Recombinant) (N-His) (STJP007174)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP007383	Human ADH5 protein (Recombinant) (N-His) (STJP007383)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human CYP3A7 protein (Recombinant) (N-His) (STJP004399)

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