Human CXCL17 (C-X-C Motif Chemokine 17) Antibody Pair (STJAP00512)
General Information
| Short Description | This CXCL17 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Sheep/Sheep |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | CXCL17 |
| Gene ID | 284340 |
| Uniprot ID | CXL17_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human CXCL17 protien.Detection Immunogen: Recombinant Human CXCL17 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion. |
| Function | Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17: Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. |
| Protein Name | C-X-C Motif Chemokine 176-Cys Cxcl17Dendritic Cell And Monocyte Chemokine-Like ProteinDmcVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-X-C Motif Chemokine 17 antibody pair6-Cys Cxcl17 antibody pairDendritic Cell And Monocyte Chemokine-Like Protein antibody pairDmc antibody pairVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 antibody pairCXCL17 antibody pairVCC1 antibody pairUNQ473 antibody pairPRO842 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human CXCL17 (C-X-C Motif Chemokine 17) Antibody Pair (STJAP00512)
This antibody pair detects human CXCL17 (C-X-C Motif Chemokine 17), corresponding to UniProt entry Q6UXB2. Reactivity is confirmed for human samples only.
The capture antibody is supplied unconjugated, while the detection antibody is biotin-conjugated. Both are sheep-raised, antigen affinity-purified antibodies provided at 0.5 mg/mL.
This pair has been validated for use in ELISA. No other assay formats are specified in the product documentation.
Recommended sample types include serum, plasma, and other biological fluids. This product is for research use only and is not intended for diagnostic or therapeutic applications.
The capture antibody is formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5. Both components should be stored at -20°C for long-term storage, and freeze-thaw cycles should be avoided.
Both the capture and detection antibodies were raised against recombinant human CXCL17 protein. Both antibodies were subsequently purified by antigen affinity chromatography.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.