Tissue Specificity | Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow. |
Post Translational Modifications | Glycosylated. |
Function | Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. |
Protein Name | C-X-C Motif Chemokine 16Scavenger Receptor For Phosphatidylserine And Oxidized Low Density LipoproteinSr-PsoxSmall-Inducible Cytokine B16Transmembrane Chemokine Cxcl16 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSecretedAlso Exists As A Soluble Form |
Alternative ELISA Names | C-X-C Motif Chemokine 16 ELISA kitScavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein ELISA kitSr-Psox ELISA kitSmall-Inducible Cytokine B16 ELISA kitTransmembrane Chemokine Cxcl16 ELISA kitCXCL16 ELISA kitSCYB16 ELISA kitSRPSOX ELISA kitUNQ2759 ELISA kitPRO6714 ELISA kit |
output | |
Information sourced from Uniprot.org