| Short Description : | Recombinant-Human CXC-chemokine receptor 1/CXCR1-C-hFc protein was developed in human using the region Met1-Lys39. For use in research applications. |
| Host: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.01 EU/ug of the protein by LAL method |
| Gene Symbol: | CXCR1 |
| Gene ID: | 3577 |
| Uniprot ID: | CXCR1_HUMAN |
| Immunogen: | Recombinant Recombinant Human CXC-chemokine receptor 1/CXCR1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Lys39) of Human CXC-chemokine receptor 1/CXCR1 (Accession #NP_000625.1) fused with |
| Immunogen Region: | Met1-Lys39 |
| Immunogen Sequence: | MSNITDPQMWDFDDLNFTGM PPADEDYSPCMLETETLNK |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. |
| Protein Name | C-X-C Chemokine Receptor Type 1Cxc-R1Cxcr-1Cdw128aHigh Affinity Interleukin-8 Receptor AIl-8r AIl-8 Receptor Type 1Cd Antigen Cd181 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | C-X-C Chemokine Receptor Type 1 proteinCxc-R1 proteinCxcr-1 proteinCdw128a proteinHigh Affinity Interleukin-8 Receptor A proteinIl-8r A proteinIl-8 Receptor Type 1 proteinCd Antigen Cd181 proteinCXCR1 proteinCMKAR1 proteinIL8RA protein |
Information sourced from Uniprot.org
