Human CTSB protein (Recombinant) (C-His) (STJP015506)

Name: Human CTSB protein (Recombinant) (C-His) (STJP015506)
SKU: STJP015506
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ImmunogenHomo sapiens (Human)

STJP015506

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Short Description	Recombinant-Human CTSB-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	Please contact us for further information.

Function	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
Protein Name	Cathepsin B App Secretase Apps Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1679131 Reactome: R-HSA-2022090 Reactome: R-HSA-2132295 Reactome: R-HSA-6798695
Cellular Localisation	Lysosome Melanosome Secreted Extracellular Space Apical Cell Membrane Peripheral Membrane Protein Extracellular Side Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Protein Names	Cathepsin B protein App Secretase protein Apps protein Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain protein CTSB protein CPSB protein

Information sourced from Uniprot.org