Human CTDSP1 protein (Recombinant) (His-Tag) (STJP017149)

Name: Human CTDSP1 protein (Recombinant) (His-Tag) (STJP017149)
SKU: STJP017149
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017149

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Short Description	Recombinant-Human CTDSP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% Glycerol, 0.1M NaCl
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	CTDSP1
Gene ID	58190
Uniprot ID	CTDS1_HUMAN
Accession Number	NP_872580
Immunogen	Human
Immunogen Region	1-260aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MDSSAVITQI SKEEARGPLR GKGDQKSAAS QKPRSRGILH SLFCCVCRDD GEALPAHSGA PLLVEENGAI PKTPVQYLLP EAKAQDSDKI CVVIDLDETL VHSSFKPVNN ADFIIPVEID GVVHQVYVLK RPHVDEFLQR MGELFECVLF TASLAKYADP VADLLDKWGA FRARLFRESC VFHRGNYVKD LSRLGRDLRR VLILDNSP

Tissue Specificity	Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
Function	Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Protein Name	Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 Nuclear Lim Interactor-Interacting Factor 3 Nli-If Nli-Interacting Factor 3 Small C-Terminal Domain Phosphatase 1 Scp1 Small Ctd Phosphatase 1
Database Links
Cellular Localisation	Nucleus Colocalizes With Rna Polymerase Ii
Alternative Protein Names	Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 protein Nuclear Lim Interactor-Interacting Factor 3 protein Nli-If protein Nli-Interacting Factor 3 protein Small C-Terminal Domain Phosphatase 1 protein Scp1 protein Small Ctd Phosphatase 1 protein CTDSP1 protein NIF3 protein NLIIF protein SCP1 protein

Information sourced from Uniprot.org