Human CTBP1 protein (Recombinant) (N-His) (STJP005322)

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STJP005322
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CTBP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CTBP1
Gene ID: 1487
Uniprot ID: CTBP1_HUMAN
Immunogen Region: Met1-Phe250
Immunogen: Homo sapiens (Human)
Post Translational Modifications The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. ADP-ribosylated.when cells are exposed to brefeldin A. Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.
Function Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Protein Name C-Terminal-Binding Protein 1
Ctbp1
Database Links Reactome: R-HSA-3769402
Reactome: R-HSA-3899300
Reactome: R-HSA-4641265
Reactome: R-HSA-5339700
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names C-Terminal-Binding Protein 1 protein
Ctbp1 protein
CTBP1 protein
CTBP protein

Information sourced from Uniprot.org

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