Human CSF2RA/GM-CSF R alpha/CD116 protein (Recombinant) (C-His&Avi) {Biotin} (STJP019960)

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STJP019960-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Biotin
Formulation: Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: CSF2RA
Gene ID: 1438
Uniprot ID: CSF2R_HUMAN
Immunogen Region: Glu23-Gly320
Immunogen: Biotinylated Recombinant Human CSF2RA/GM-CSF R alpha/CD116 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu23-Gly320) of Human CSF2RA/GM-CSF R alpha/CD116 (Accession #P15509-1) fused with a C-H
Immunogen Sequence: EKSDLRTVAPASSLNVRFDS RTMNLSWDCQENTTFSKCFL TDKKNRVVEPRLSNNECSCT FREICLHEGVTFEVHVNTSQ RGFQQKLLYPNSGREGTAAQ NFSCFIYNADLMNCTWARGP TAPRDVQYFLYIRNSKRRRE IRCPYYIQDSGTHVGCHLDN LSGLTSRNYFLVNGTSREIG IQFFDSLLDTKKIERFNPPS NVTVRCNTTHCLVRWKQPRT YQKLSYLDFQYQLDVHRKN
Function Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Protein Name Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha
Gm-Csf-R-Alpha
Gmcsfr-Alpha
Gmr-Alpha
Cdw116
Cd Antigen Cd116
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-5683826
Reactome: R-HSA-5688849
Reactome: R-HSA-5688890
Reactome: R-HSA-912526
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Secreted
Isoform 4: Secreted
Isoform 6: Secreted
Alternative Protein Names Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha protein
Gm-Csf-R-Alpha protein
Gmcsfr-Alpha protein
Gmr-Alpha protein
Cdw116 protein
Cd Antigen Cd116 protein
CSF2RA protein
CSF2R protein
CSF2RY protein

Information sourced from Uniprot.org

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