Human Crystallin beta B1/CRYBB1 protein (Recombinant) (His-Tag) (STJP016724)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Crystallin beta B1/CRYBB1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRYBB1 |
| Gene ID | 1414 |
| Uniprot ID | CRBB1_HUMAN |
| Accession Number | NP_001878 |
| Immunogen | Human |
| Immunogen Region | 1-252aa |
| Immunogen Sequence | MSQAAKASAS ATVAVNPGPD TKGKGAPPAG TSPSPGTTLA PTTVPITSAK AAELPPGNYR LVVFELENFQ GRRAEFSGEC SNLADRGFDR VRSIIVSAGP WVAFEQSNFR GEMFILEKGE YPRWNTWSSS YRSDRLMSFR PIKMDAQEHK ISLFEGANFK GNTIEIQGDD APSLWVYGFS DRVGSVKVSS GTWVGYQYPG YRGYQYLLEP GDFRHWNEWG AFQPQMQS |
Additional Info
| Post Translational Modifications | Specific cleavages in the N-terminal arm occur during lens maturation and give rise to truncated forms, leading to impaired oligomerization and protein insolubilization. |
| Function | Crystallins are the dominant structural components of the vertebrate eye lens. |
| Protein Name | Beta-Crystallin B1Beta-B1 Crystallin |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Beta-Crystallin B1 proteinBeta-B1 Crystallin proteinCRYBB1 protein |
Information sourced from Uniprot.org