Human CPLX2 protein (Recombinant) (N-His) (STJP005591)

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STJP005591
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CPLX2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CPLX2
Gene ID: 10814
Uniprot ID: CPLX2_HUMAN
Immunogen Region: Asp2-Lys134
Immunogen: Homo sapiens (Human)
Function Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis.
Protein Name Complexin-2
Complexin Ii
Cpx Ii
Synaphin-1
Cellular Localisation Cytoplasm
Cytosol
Presynapse
Nucleus
Perikaryon
Translocated From The Perikaryon To The Presynaptic Terminals During Maturation Of Neuronal Cells
In Mast Cells
Cytosol And Nucleus
Becomes Enriched Near Plasma Membrane Following Stimulation
Alternative Protein Names Complexin-2 protein
Complexin Ii protein
Cpx Ii protein
Synaphin-1 protein
CPLX2 protein

Information sourced from Uniprot.org

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