| Short Description : | Recombinant-Human CNTFR alpha-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNTFR |
| Gene ID: | 1271 |
| Uniprot ID: | CNTFR_HUMAN |
| Accession Number: | NP_001833 |
| Immunogen: | Human |
| Immunogen Region: | 23-342aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MQRHSPQEAP HVQYERLGSD VTLPCGTANW DAAVTWRVNG TDLAPDLLNG SQLVLHGLEL GHSGLYACFH RDSWHLRHQV LLHVGLPPRE PVLSCRSNTY PKGFYCSWHL PTPTYIPNTF NVTVLHGSKI MVCEKDPALK NRCHIRYMHL FSTIKYKVSI SVSNALGHNA TAITFDEFTI VKPDPPENVV ARPVPSNPRR LEVTWQTP |
| Tissue Specificity | Nervous system and skeletal muscle. |
| Function | Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1. |
| Protein Name | Ciliary Neurotrophic Factor Receptor Subunit AlphaCntf Receptor Subunit AlphaCntfr-Alpha |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Ciliary Neurotrophic Factor Receptor Subunit Alpha proteinCntf Receptor Subunit Alpha proteinCntfr-Alpha proteinCNTFR protein |
Information sourced from Uniprot.org
