Tissue Specificity | CNP-22: In the kidney, predominantly expressed in the distal tubular cells (at protein level). |
Post Translational Modifications | CNP-22: Degraded by IDE (in vitro). |
Function | CNP-22: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Acts by specifically binding and stimulating NPR2 to produce cGMP. Binds the clearance receptor NPR3. |
Protein Name | C-Type Natriuretic Peptide Cleaved Into - Cnp-22 - Cnp-29 - Cnp-53 |
Database Links | Reactome: R-HSA-5578768 |
Cellular Localisation | Secreted |
Alternative ELISA Names | C-Type Natriuretic Peptide Cleaved Into - Cnp-22 - Cnp-29 - Cnp-53 ELISA kitNPPC ELISA kitCNP2 ELISA kit |
output | |
Information sourced from Uniprot.org