Human CLPP protein (Recombinant) (N-His) (STJP007415)

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STJP007415
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CLPP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CLPP
Gene ID: 8192
Uniprot ID: CLPP_HUMAN
Immunogen Region: Gly21-His247
Immunogen: Homo sapiens (Human)
Function Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion.
Protein Name Atp-Dependent Clp Protease Proteolytic Subunit - Mitochondrial
Endopeptidase Clp
Database Links Reactome: R-HSA-9837999
Cellular Localisation Mitochondrion Matrix
Alternative Protein Names Atp-Dependent Clp Protease Proteolytic Subunit - Mitochondrial protein
Endopeptidase Clp protein
CLPP protein

Information sourced from Uniprot.org