Human CLEC4M (C-type lectin domain family 4 member M) Sandwich ELISA Kit (STJE0020129)

SKU:
STJE0020129-96
£444.50
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Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 1.875 ng/mL
Detection Limit: 3.125-200 ng/mL
Storage Instruction: Store unopened box at 2-8 °C for up to 1 month. For longer storage check individual components.
Assay Time: 4 hours
Gene Symbol: CLEC4M
Gene ID: 10332
Uniprot ID: CLC4M_HUMAN
Specificity: This Sandwich ELISA kit recognizes Human C-type lectin domain family 4 member M in various sample types. No significant cross-reactivity or interference was observed between Human CLEC4M analogues.
Sample Type: Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Tissue Specificity Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells.
Post Translational Modifications
Function Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for Ebolavirus. (Microbial infection) Acts as an attachment receptor for Hepatitis C virus. (Microbial infection) Acts as an attachment receptor for HIV-1. (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E. (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5. (Microbial infection) Acts as an attachment receptor for Influenzavirus. (Microbial infection) Acts as an attachment receptor for SARS-CoV. (Microbial infection) Acts as an attachment receptor for West-nile virus. (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus. (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein. (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule.
Protein Name C-Type Lectin Domain Family 4 Member M
Cd209 Antigen-Like Protein 1
Dc-Sign-Related Protein
Dc-Signr
Dendritic Cell-Specific Icam-3-Grabbing Non-Integrin 2
Dc-Sign2
Liver/Lymph Node-Specific Icam-3-Grabbing Non-Integrin
L-Sign
Cd Antigen Cd299
Database Links Reactome: R-HSA-9833110
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type Ii Membrane Protein
Isoform 2: Cell Membrane
Isoform 3: Cell Membrane
Isoform 5: Secreted
Isoform 6: Secreted
Isoform 7: Secreted
Isoform 10: Secreted
Alternative ELISA Names C-Type Lectin Domain Family 4 Member M ELISA kit
Cd209 Antigen-Like Protein 1 ELISA kit
Dc-Sign-Related Protein ELISA kit
Dc-Signr ELISA kit
Dendritic Cell-Specific Icam-3-Grabbing Non-Integrin 2 ELISA kit
Dc-Sign2 ELISA kit
Liver/Lymph Node-Specific Icam-3-Grabbing Non-Integrin ELISA kit
L-Sign ELISA kit
Cd Antigen Cd299 ELISA kit
CLEC4M ELISA kit
CD209L ELISA kit
CD209L1 ELISA kit
CD299 ELISA kit
output

Information sourced from Uniprot.org

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