Tissue Specificity | Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord. |
Post Translational Modifications | |
Function | Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin. |
Protein Name | Carbohydrate Sulfotransferase 9Galnac-4-O-Sulfotransferase 2Galnac-4-St2Galnac4st-2N-Acetylgalactosamine-4-O-Sulfotransferase 2 |
Database Links | Reactome: R-HSA-2022870 Q7L1S5-2 |
Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinIsoform 2: Secreted |
Alternative ELISA Names | Carbohydrate Sulfotransferase 9 ELISA kitGalnac-4-O-Sulfotransferase 2 ELISA kitGalnac-4-St2 ELISA kitGalnac4st-2 ELISA kitN-Acetylgalactosamine-4-O-Sulfotransferase 2 ELISA kitCHST9 ELISA kitUNQ2549 ELISA kitPRO6175 ELISA kit |
output | |
Information sourced from Uniprot.org