Human CHRNa7 (Cholinergic Receptor, Nicotinic, Alpha 7) Sandwich ELISA Kit Kit (STJE0007943)

Human CHRNa7 (Cholinergic Receptor, Nicotinic, Alpha 7) Sandwich ELISA Kit Kit (STJE0007943)

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STJE0007943
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.112ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This CHRNa7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CHRNA7
Gene ID: 1139/89832
Uniprot ID: ACHA7_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Glycosylations at Asn-46, Asn-90 and Asn-133 are essential for TMEM35A/NACHO-mediated proper subunit assembly and trafficking to the cell membrane.
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
Protein Name Neuronal Acetylcholine Receptor Subunit Alpha-7
Database Links Reactome: R-HSA-629594
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Tmem35a/Nacho Promotes Its Trafficking To The Cell Membrane
Ric3 Promotes Its Trafficking To The Cell Membrane
Alternative ELISA Names Neuronal Acetylcholine Receptor Subunit Alpha-7 ELISA kit
CHRNA7 ELISA kit
NACHRA7 ELISA kit
output

Information sourced from Uniprot.org

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