| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CHRNA3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | CHRNA3 |
| Gene ID: | 1136 |
| Uniprot ID: | ACHA3_HUMAN |
| Immunogen Region: | Ser32-Leu240 |
| Immunogen: | Homo sapiens (Human) |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Protein Name | Neuronal Acetylcholine Receptor Subunit Alpha-3 |
| Database Links | Reactome: R-HSA-629587Reactome: R-HSA-629594Reactome: R-HSA-629597 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell MembraneEndoplasmic ReticulumGolgi ApparatusInteraction With Ubxn2a/Ubxd4 Promotes Translocation To The Plasma Membrane |
| Alternative Protein Names | Neuronal Acetylcholine Receptor Subunit Alpha-3 proteinCHRNA3 proteinNACHRA3 protein |
Information sourced from Uniprot.org
