Human CHRNA3 protein (Recombinant) (N-His) (STJP004562)

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STJP004562
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CHRNA3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CHRNA3
Gene ID: 1136
Uniprot ID: ACHA3_HUMAN
Immunogen Region: Ser32-Leu240
Immunogen: Homo sapiens (Human)
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Protein Name Neuronal Acetylcholine Receptor Subunit Alpha-3
Database Links Reactome: R-HSA-629587
Reactome: R-HSA-629594
Reactome: R-HSA-629597
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Endoplasmic Reticulum
Golgi Apparatus
Interaction With Ubxn2a/Ubxd4 Promotes Translocation To The Plasma Membrane
Alternative Protein Names Neuronal Acetylcholine Receptor Subunit Alpha-3 protein
CHRNA3 protein
NACHRA3 protein

Information sourced from Uniprot.org