Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human CHRNA1-C-His protein was developed from e. coli and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | CHRNA1 |
Gene ID: | 1134 |
Uniprot ID: | ACHA_HUMAN |
Immunogen Region: | Ser21-LeuL255 |
Immunogen: | Homo sapiens (Human) |
Function | Isoform 1: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Isoform 2: Non functional acetylcholine receptor alpha subunit which is not integrated into functional acetylcholine-gated cation-selective channels. |
Protein Name | Acetylcholine Receptor Subunit Alpha |
Database Links | Reactome: R-HSA-629594Reactome: R-HSA-629597 |
Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
Alternative Protein Names | Acetylcholine Receptor Subunit Alpha proteinCHRNA1 proteinACHRA proteinCHNRA protein |
Information sourced from Uniprot.org