Human CHRDL1 (Chordin Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014308)

Human CHRDL1 (Chordin Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014308)

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STJE0014308
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.054ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This CHRDL1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CHRDL1
Gene ID: 91851
Uniprot ID: CRDL1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in the developing cornea and in the eye anterior segment in addition to the retina. Differentially expressed in the fetal brain. There is high expression in cerebellum and neocortex. Expressed in retinal pericytes.
Post Translational Modifications
Function Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation. May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Protein Name Chordin-Like Protein 1
Neuralin-1
Neurogenesin-1
Ventroptin
Database Links Reactome: R-HSA-201451
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative ELISA Names Chordin-Like Protein 1 ELISA kit
Neuralin-1 ELISA kit
Neurogenesin-1 ELISA kit
Ventroptin ELISA kit
CHRDL1 ELISA kit
NRLN1 ELISA kit
output

Information sourced from Uniprot.org

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