| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CFHR1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 8% Trehalose, 4% Mannitol, 50mM NaCl, 0.05% Tween 80, pH 7.5. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | CFHR1 |
| Gene ID: | 3078 |
| Uniprot ID: | FHR1_HUMAN |
| Immunogen Region: | Glu19-Arg330 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | N-glycosylated. Two forms are observed.one with a single side chain and the other with two. |
| Function | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
| Protein Name | Complement Factor H-Related Protein 1Fhr-1H Factor-Like Protein 1Fhl-1H-Factor-Like 1H36 |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Complement Factor H-Related Protein 1 proteinFhr-1 proteinH Factor-Like Protein 1 proteinFhl-1 proteinH-Factor-Like 1 proteinH36 proteinCFHR1 proteinCFHL proteinCFHL1 proteinCFHL1P proteinCFHR1P proteinFHR1 proteinHFL1 proteinHFL2 protein |
Information sourced from Uniprot.org
