| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 25mM NaAc pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g |
| Gene Symbol: | CER1 |
| Gene ID: | 9350 |
| Uniprot ID: | CER1_HUMAN |
| Immunogen Region: | Thr18-Ala267 |
| Immunogen: | Recombinant Human CER1/DAND4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr18-Ala267) of human CER1/DAND4 (Accession #NP_005445.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | TRHQDGRQNQSSLSPVLLPR NQRELPTGNHEEAEEKPDLF VAVPHLVATSPAGEGQRQRE KMLSRFGRFWKKPEREMHPS RDSDSEPFPPGTQSLIQPID GMKMEKSPLREEAKKFWHHF MFRKTPASQGVILPIKSHEV HWETCRTVPFSQTITHEGCE KVVVQNNLCFGKCGSVHFPG AAQHSHTSCSHCLPAKFTTM HLPLNCTELSSVIKVVMLVE ECQCKVKTEHEDGHILHAG |
| Function | Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. |
| Protein Name | CerberusCerberus-Related ProteinDan Domain Family Member 4 |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1433617Reactome: R-HSA-201451 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cerberus proteinCerberus-Related Protein proteinDan Domain Family Member 4 proteinCER1 proteinDAND4 protein |
Information sourced from Uniprot.org